产前超声检查对胎儿卵圆孔血流受限或提前闭合的诊断价值 [中文引用][英文引用]

目的 分析产前超声检查对胎儿卵圆孔血流受限、提前闭合（FO-R/C）的诊断价值。方法 选取本院收治的胎儿卵圆孔血流受限或提前闭合孕妇29例作为观察组，选取同期健康胎儿孕妇33例作为对照组，对两组临床资料进行回顾性分析，观察产前超声检查的结果，并进行对比分析。结果 观察组孕妇29例，其中2例在孕周26周时，确诊胎儿卵圆孔血流受限或提前闭合，剩余27例孕妇均在孕周30周后确诊。胎儿卵圆孔内径在3mm内21例，平均胎儿卵圆孔内径（1.7±0.6）mm，剩余8例胎儿卵圆孔近闭合。经检查后发现，29例三尖瓣均有不同程度的反流信号，其中11例有少量的心包腔积液，3例有心包腔积液合并腹腔积液。29例产前超声检查结果显示，右心增大，但左心比例缩小，主动脉内径与肺动脉内径比较，主动脉内径较细，主动脉瓣启闭很好。观察组RV/LV、MPA/AO、RA/LA、VMPA/VOA、心胸比水平均高于对照组，差异均有统计学意义（P＜0.05）。结论 产前超声检查对胎儿卵圆孔血流受限、提前闭合的诊断价值较高，可提高FO-R/C胎儿的存活率。

Objective To analyze the value of prenatal ultrasound in the diagnosis of fetal oval foramen flow limitation and early closure（FO-R/C）. Methods 29 cases of pregnant women with fetal oval foramen flow limitation and early closure treated in our hospital were selected as the observation group and 33 healthy pregnant women in the same period were selected as the control group. The clinical data of two groups were analyzed retrospectively, and the results of prenatal ultrasound examination were observed and the comparative analysis was carried out. Results 2 cases of the 29 cases of pregnant women in the observation group were diagnosed with confinement of fetal oval foramen flow or early closure at 26 weeks gestational age, but the remaining 27 cases of pregnant women were diagnosed with the same disease at 30 weeks gestational age. There were 21 cases whose inner diameter of the foramen oval was in 3mm. The average diameter of the fetal oval hole was（1.7 + 0.6）mm, and the remaining 8 cases of fetal oval foramen were nearly closed. After examination, the three cusp valves in 29 cases had different degrees of regurgitation signals, of which 11 cases had a small amount of pericardial effusion, and 3 cases had cardiac pericardial effusion and celiac effusion. The results of prenatal ultrasound examination in 29 cases showed that the right heart was enlarged but the ratio of the left heart was narrowed and that the internal diameter of the aorta was relatively thinner but the opening and closing of the aortic valve was very good, compared the internal diameter of the aorta with the diameter of the pulmonary artery. The average value of RV/LV, MPA/AO, RA/LA,VMPA/VOA, and cardiothoracic ratio level in the observation group were higher than those of the control group, and the difference was statistically significant（P < 0.05）. Conclusions The prenatal ultrasound examination is of high value in the diagnosis of confinement of fetal oval foramen flow and early closure, which can improve the survival rate of FO-R/C fetus.