目的 探讨脐血流值对妊娠合并血小板减少妊娠终止时机的指导价值。方法 随机选取我院诊治的妊娠合并血小板减少孕妇60例，根据脐血流值S/D分为观察组（S/D≥2.5）和对照组（S/D<2.5），对两组孕妇的临床资料包括胎心、终止妊娠时间、妊娠结局、产后出血率、血小板减少程度、出生时Apgar评分等数据进行回顾性分析，并对出生1个月心功能进行随访。结果 观察组术前血小板计数为（51.33±6.22）×109/L，与对照组比较差异无统计学意义（P＞0.05）但产时出血量明显高于对照组，其中出血量≥500mL有5例，组间差异具有统计学意义（P<0.05）；观察组的平均妊娠时间（38.33±6.33）周，与对照组比较差异无统计学意义（P＞0.05），但早产率和剖宫产率均明显高于对照组，同时新生儿评分亦优于对照组，组间比较差异具有统计学意义（P<0.05）。结论 对于妊娠合并血小板减少的孕妇，监测脐血流值对终止妊娠时机的选择和改善妊娠结局均具有重要意义。
Objective To explore the guiding value of umbilical cord blood flow on the termination of pregnancy with thrombocytopenia. Method Randomly selected from our hospital diagnosis and treatment of pregnancy with thrombocytopenia pregnant women 60 cases, according to the umbilical cord blood flow S/D value can be divided into observation group (S/D≥2.5) and control group (S/D<2.5), the clinical data of two groups of pregnant women including heart, time termination of pregnancy, the pregnancy outcome, postpartum hemorrhage rate, degree of thrombocytopenia, Apgar score at birth and other data were retrospectively analyzed, and the heart function was born a month follow-up. Results The preoperative platelet count of the observation group was（51.33±6.22）×109/L, which was not statistically significant compared with the control group (P>0.05), but the amount of bleeding at birth was significantly higher than that of the control group, and there were 5 cases with the amount of bleeding greater than or equal to 500mL, and the difference between the two groups was statistically significant (P<0.05). The mean gestational time of the observation group（38.33±6.33）weeks was not statistically significant compared with that of the control group (P>0.05), but the preterm delivery rate and cesarean section rate were significantly higher than those of the control group, and the neonatal score was also better than that of the control group, and the difference between the two groups was statistically significant (P<0.05). Conclusions For pregnant women with thrombocytopenia during pregnancy, monitoring umbilical cord blood flow is of great significance to the timing of termination of pregnancy and the improvement of pregnancy outcome.
